Genetic linkage analysis
Kyazma ® focuses on genetic linkage analysis in diploid experimental populations. JoinMap ® is Kyazma's software product for computing genetic linkage maps and MapQTL ® is its software for linkage analysis of quantitative traits. The two products have their origins in plant genetics. They are utilized broadly in genetic research of many plant species. In early versions of the software, their methods were extended for the analysis of single full-sib families of outbreeding species. This enhanced the genetic linkage analysis in, for example, many fruit tree and forest tree species. Because this family type is not limited to plant species alone, the software has found its way to the genetic research of many other species than plants, for example fish, amphibians and crustaceans.
Expected release of version 7 of MapQTL ®
[18 August 2023]
By the end of October the release of the next version of MapQTL is expected.
While preserving the user interface, the methods and the workflow with the program on the whole, v7 has many enhancements over v6, several of which are quite significant. Most are intended as improvements for working with larger datasets of genetic markers and traits. Major efforts have gone into increasing the computational speeds of the analyses, with success. In brief, the main technical improvements are: (a) the change towards 64 bit software, (b) the redesign of various probability computations, (c) the use of an embedded database system for storing all data, and (d) the parallelization of various calculations. The user interface was adjusted to improve the dealing with many phenotypic traits.
Two methods were added: the traits scan and the epistasis test. The traits scan method performs a condensed analysis of a large number of quantitative traits based on interval mapping. The epistasis test makes it possible to investigate the presence of epistatic interaction between two loci.
As soon as the release date becomes known, it will be possible to start ordering MapQTL 7. Ordering an upgrade with a discount will be available, if you have a license of MapQTL version 6.
Maintenance update of MapQTL ® 6
[10 October 2022]
An update of MapQTL 6 was released. Please, check out the release notes.
Maintenance update of JoinMap ® 5
[7 October 2022]
An update of JoinMap 5 was released. Please, check out the release notes.
Genetic Mapping in Experimental Populations
Authors: J.W. Van Ooijen & J. Jansen
Publisher: Cambridge University Press
Date: August 2013
This concise introduction to genetic mapping in diploid species teaches the theory behind map construction, explains the computations involved at each stage, and provides exercises and problem solving tips. It will enable graduate students and researchers in the life sciences to employ methods effectively and to achieve more reliable results.
• Practical coverage enables readers to effectively use the currently available software for achieving more reliable results
• Includes a description of eight of the most common map ordering algorithms
• Contains a detailed explanation on map construction in an outbreeding species full-sib family
• Written specifically for life science researchers; does not assume any background in mathematics or statistics
- General information:
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About Kyazma ®
The company was founded in the spring of 2003. It has taken over the development, distribution and support of the software packages JoinMap ® and MapQTL ® from Biometris of Wageningen UR. Kyazma focuses on implementing the latest powerful statistical genomics methods into easy to use, stable and fast software.
Statistical genomics develops powerful methods for genetical linkage mapping and QTL analysis. These methods are usually too specialised, too technical in statistics, for the many experimental geneticists and molecular biologists to thoroughly understand. It is here that Kyazma wants to assist with software tools that provide easy-as-possible access to statistical genomics methods.