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Genetic linkage analysis

Kyazma ® focuses on genetic linkage analysis in diploid experimental populations. JoinMap ® is Kyazma's software product for computing genetic linkage maps and MapQTL ® is its software for linkage analysis of quantitative traits. The two products have their origins in plant genetics. They are utilized broadly in genetic research of many plant species. In early versions of the software, their methods were extended for the analysis of single full-sib families of outbreeding species. This enhanced the genetic linkage analysis in, for example, many fruit tree and forest tree species. Because this family type is not limited to plant species alone, the software has found its way to the genetic research of many other species than plants, for example fish, amphibians and crustaceans. In addition to producing software, Kyazma teaches introductory courses on genetic linkage mapping and QTL analysis.

Announcements:

• JoinMap ® version 5 – Final edition released!

[5 January 2019]
The final edition of JoinMap v5 is released. The new version 5 builds on its predecessor, v4.1, preserving the user interface and workflow with the program on the whole. Most enhancements over v4.1 are improvements for working with very large sets of genetic markers. In brief, the major technical improvements are: (a) the change towards 64-bit software, (b) the use of an embedded database system for storing all data, and (c) the parallelization of some calculations. In addition to these technical improvements, several aspects of the various algorithms and the user interface are enhanced.

The change to 64-bit allows access to more system memory, which is useful for very large datasets. Using an embedded database system greatly improves the responsiveness of the user interface with large datasets. Finally, parallelization increases the computational speed on systems with a multi-core processor, of which all available computational cores can be utilized.

Upgrade discounts are available for owners of licenses for version 4 and version 4.1.

• Plant & Animal Genome XXVII Conference, 12-16 January 2019

Kyazma will be present at the next PAG Conference in San Diego, CA, USA. Visit Kyazma's booth (nr. 617) in the Grand Exhibit Hall, or come to a workshop session on Monday 14th, 12:50 pm - 3:00 pm, Pacific Salon 4 and 5, where live demonstrations of JoinMap and MapQTL will be given.

• Maintenance updates of JoinMap ® 4 and 4.1

[31 July 2013]
Updates of JoinMap 4 and 4.1 were released with a useful new feature: a new Grouping node menu function 'Assign Identical Loci to Their Groups'. Please read more about the details in the Release notes. The updates are available for free for licensed users.

• Maintenance update of MapQTL ® 6

[12 March 2013]
An update of MapQTL 6 was released that corrects an error in IM and MQM analyses on BCBxFy populations.

• Textbook hint:

book cover image

Genetic Mapping in Experimental Populations

Authors: J.W. Van Ooijen & J. Jansen
Publisher: Cambridge University Press
Date: August 2013

This concise introduction to genetic mapping in diploid species teaches the theory behind map construction, explains the computations involved at each stage, and provides exercises and problem solving tips. It will enable graduate students and researchers in the life sciences to employ methods effectively and to achieve more reliable results.

Key features:
• Practical coverage enables readers to effectively use the currently available software for achieving more reliable results
• Includes a description of eight of the most common map ordering algorithms
• Contains a detailed explanation on map construction in an outbreeding species full-sib family
• Written specifically for life science researchers; does not assume any background in mathematics or statistics

Order with Cambridge University Press or with Amazon.