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Genetic linkage analysis

Kyazma ® focuses on genetic linkage analysis in diploid experimental populations. JoinMap ® is Kyazma's software product for computing genetic linkage maps and MapQTL ® is its software for linkage analysis of quantitative traits. The two products have their origins in plant genetics. They are utilized broadly in genetic research of many plant species. In early versions of the software, their methods were extended for the analysis of single full-sib families of outbreeding species. This enhanced the genetic linkage analysis in, for example, many fruit tree and forest tree species. Because this family type is not limited to plant species alone, the software has found its way to the genetic research of many other species than plants, for example fish, amphibians and crustaceans.

Maintenance update of JoinMap ® 5

[19 January 2024]
An update of JoinMap 5 was released. Please, check out the release notes.

Release of version 7 of MapQTL ®

[23 October 2023]
Today the final release was made of the new MapQTL version 7.

While preserving most of the user interface, the methods and the general workflow with the program, version 7 has many enhancements over version 6, several of which are quite significant. Most are intended as improvements for working with larger datasets of genetic markers and traits. Major efforts have gone into increasing the computational speeds of the analyses, with success. In brief, the main technical improvements are: (a) the change towards 64-bit software, (b) the redesign of various probability computations, (c) the use of an embedded database system for storing all data, and (d) the parallelization of various calculations. The user interface was adjusted to improve the dealing with many phenotypic traits.

Two methods were added: the traits scan and the epistasis test. The traits scan method performs a condensed analysis of a large number of quantitative traits based on interval mapping. The epistasis test investigates the presence of epistatic interaction between two loci.

From today it is possible to order licenses for MapQTL 7. Ordering a license upgrade with a discount will be available, if you have a license for MapQTL version 6.

Read more ...

Maintenance update of MapQTL ® 6

[10 October 2022]
An update of MapQTL 6 was released. Please, check out the release notes.

Textbook hint:

book cover image

Genetic Mapping in Experimental Populations

Authors: J.W. Van Ooijen & J. Jansen
Publisher: Cambridge University Press
Date: August 2013

This concise introduction to genetic mapping in diploid species teaches the theory behind map construction, explains the computations involved at each stage, and provides exercises and problem solving tips. It will enable graduate students and researchers in the life sciences to employ methods effectively and to achieve more reliable results.

Key features:
• Practical coverage enables readers to effectively use the currently available software for achieving more reliable results
• Includes a description of eight of the most common map ordering algorithms
• Contains a detailed explanation on map construction in an outbreeding species full-sib family
• Written specifically for life science researchers; does not assume any background in mathematics or statistics

Order with Cambridge University Press or with Amazon.

Contact information


      General information:

      +31 652 363 242 (mobile)
        (Time zone CEST: GMT + 2 hr;   current time in Wageningen: 20:02:24)

      Kyazma B.V.
      Ln.v.A. Pieck 6
      6708RE Wageningen

About Kyazma ®

The company was founded in the spring of 2003. It has taken over the development, distribution and support of the software packages JoinMap ® and MapQTL ® from Biometris of Wageningen UR. Kyazma focuses on implementing the latest powerful statistical genomics methods into easy to use, stable and fast software.

Statistical genomics develops powerful methods for genetical linkage mapping and QTL analysis. These methods are usually too specialised, too technical in statistics, for the many experimental geneticists and molecular biologists to thoroughly understand. It is here that Kyazma wants to assist with software tools that provide easy-as-possible access to statistical genomics methods.

Registrations of Kyazma ®

Netherlands VAT number: NL811805116B01
Netherlands Chamber of Commerce registration number: 09134959
D&B D-U-N-S ® number: 408556582